Mealtime Is NONO Speckled: Timing Hepatic Adaptation to Food

Abstract

You are what you eat; but when you eat also seems to be important for a healthy metabolism. In this issue of Cell Metabolism, Benegiamo etal. (2018) uncover a mechanism by which the RNA-binding protein NONO promotes the time-of-day-dependent expression of key metabolic genes at a post-transcriptional level in response to nutrition.