ME03 How to treat recurrent or metastatic nasopharyngeal cancer?

Abstract

Locoregional recurrence of NPC is uncommon in the era of Intensity Modulated Radiation Therapy (IMRT). Salvage surgery should be considered and salvage neck dissection is preferred in isolated regional relapse. Re-irradiation is associated with significant morbidities but local control rates of greater than or equal to 50% can be obtained at 1-2 years. In patients with oligometastatic disease, local treatments with stereotactic body RT, metastasectomy and radiofrequency ablation can be used. The prognosis of recurrent metastatic (R/M) NPC is heterogeneous.