Abstract

Objectives:To evaluate the surgical feasibility and the long-term anatomical and functional results and complication rates in patients with Mullerian aplasia who underwent vaginal reconstruction.Methods:A retrospective observational case series study over 8 years was conducted in King Faisal Specialist Hospital & Research Centre – Jeddah, Saudi Arabia. All cases diagnosed as Mullerian aplasia and who underwent surgical correction were included. Painless and satisfactory vaginal intercourse after surgery were the main outcome measured.Results:A total of 19 patients were diagnosed with Mullerian agenesis and underwent vaginal reconstruction by Mclndoe technique with minor modification. All of our patients who were sexually active and were compliant with mold use postoperatively were able to achieve 100% painless and satisfactory sexual intercourse.Conclusions:Minor modification in McIndoe technique provides easier, safer and deeper dissection that minimizes the complications and helps in maximizing the vaginal length. It provides satisfactory and functional vagina in the majority of the patients.

Highlights

  • Mullerian agenesis named as Mullerian aplasia, Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome or Vaginal agenesis, is a rare condition with an incidence of 1 in 4,000 to 1 in 10,000 females.[1,2]

  • A retrospective observational case series study was conducted in King Faisal Specialist Hospital & Research Centre – Jeddah, Saudi Arabia

  • All cases diagnosed as Mullerian aplasia (Mayer-RokitanskyHauser syndrome) and who underwent the surgical correction, i.e., Mclndoe technique of vaginal reconstruction with minor modification over 8 years (July 2007 June 2015) were included

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Summary

Introduction

Correspondence: November 9, 2016 December 16, 2016 can expect to encounter this condition for a few times during their professional career. It refers to the congenital aplasia or severe hypoplasia of the structures derived from the mullerian duct, including proximal 2/3 of vagina, uterus and fallopian tubes.[3] In these patients ovaries are normal in structure and endocrine function due to separate embryological origin,[1] have a normal development of secondary sexual characteristics and external genitalia with normal 46XX karyotype and hormonal profile.[1,4]

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