McIndoe Vaginoplasty: A Ray of Hope for MRKH Patients

Abstract

Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH) is caused by fetal Mullerian-duct genesis failure, which results in a congenital insufficiency of the upper vaginal wall and a rudimentary to absent uterus. These patients present with primary amenorrhea, infertility as well as difficulty in coital activity. Although conception requires IVF and surrogacy but sexual life and coital satisfaction can be initiated with neovaginal construction by McIndoe Vaginoplasty. The primary goal of this study was to create a neovagina that would lead to a satisfying sexual life. Over the course of three years, seven patients with MRKH syndrome had modified McIndoe Vaginoplasty with split thickness skin grafts, and these patients were monitored for two years. All of the patients were given extensive information about the surgery, the risks involved, and the expected outcome. All of the patients were subjected to thorough examinations. In all seven patients, the functional outcomes were satisfactory. There was no need for blood transfusion and no major complications. The average vaginal length was 7-9 cm and the average vaginal breadth was 3-4 cm. All patients' donor sites healed properly and without issues. If performed with competent surgical skills, modified McIndoe Vaginoplasty is a safe and effective technique to attain sexual happiness in patients with vaginal agenesis, with no donor site problems.