Abstract
McCune-Albright Syndrome (MAS) is a rare sporadic disease characterized by bone fibrous dysplasia, Cafe au lait spots and a variable association of hyperfunction endocrine disorders. There is not any certain treatment available for this syndrome, and both physical and emotional disability in these patients is still a major concern for physicians. In present report we have described a 10- year-old girl, presented with precocious puberty, multiple Cafe au lait macules and fibrous dysplasia, successfully treated with pamidronate in a four-year follow-up period.
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