Abstract
ABSTRACT This paper presents the results on the study of melanocortin-4 receptor (MC4R) gene polymorphisms in sheep of the Karachai breed. AA, AG, and GG genotypes were determined to have allele frequencies of 47%, 37%, and 16%, respectively, indicating that allele A and the homozygous AA genotype occurred the most frequently. Analysis of the meat productivity of sheep, with respect to the MC4R genotype, showed a higher slaughter yield in sheep with the AA genotype compared to those with either the GG or AG genotypes. The variability at these loci provides a basis for controlling the meat productivity of sheep in the Karachai sheep population; therefore, this polymorphism should be monitored and melanocortin-4 receptor (MC4R) gene selection considered in pedigree farms.
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