Maxillofacial rhabdomyosarcoma in the canine maxillofacial area

Lakshmi Gandi,S Vivekanand

doi:10.5455/vetworld.2012.565-567

Abstract

Juvenile rhabdomyosarcomas were diagnosed in two young dogs based on the results of histopathology, phosphotungstic acid-hematoxylin stain, immunohistochemistry, and the age of the dogs. One dog, an 2yrs germanshepard had tumor mass in the maxillary premolar teeth gingiva . Histologically, the gingival mass was an alveolar type of rhabdomyosarcoma . The other dog, a 1.5-year-old Basset Hound, had alveolar type of rhabdomyosarcoma involving the premolar to molar teeth region and CT examination in each case revealed extensive bony involvement of maxilla .temporal muscles, with metastasis to the regional lymph node and lungs. A diagnosis of solid-pattern alveolar rhabdomyosarcoma was made on the basis of morphologic and immunohistochemical staining for desmin. Alveolar rhabdomyosarcoma should be considered in the differential diagnosis of tumors in juvenile dogs, especially when cytologic findings reveal round, undifferentiated cells. Both the cases were subjected to surgical excision of tumor tissue followed by chemotherapy. Both the dogs died within two months of the admission.

Highlights

Rhabdomyosarcomas spontaneously arising in skeletal muscles are rare in domestic animals [1] .In humans, rhabdomyosarcoma is the most common soft tissue tumor in infants and children under 15 years of age, comprising about 50% of all childhood soft tissue neoplasm [2,3]
We describe juvenile Rhabdomyosarcomas in two young dogs an 2yrs germanshepard had tumor mass in the left maxillary premolar teeth gingiva
The gingival mass was an alveolar type of rhabdomyosarcoma

Summary

Introduction

Rhabdomyosarcomas spontaneously arising in skeletal muscles are rare in domestic animals [1] .In humans, rhabdomyosarcoma is the most common soft tissue tumor in infants and children under 15 years of age, comprising about 50% of all childhood soft tissue neoplasm [2,3]. Rhabdomyosarcomas are classified into three main types based on the histological features: pleomorphic, embryonal and alveolar [1]. We describe juvenile Rhabdomyosarcomas in two young dogs an 2yrs germanshepard had tumor mass in the left maxillary premolar teeth gingiva . The gingival mass was an alveolar type of rhabdomyosarcoma.

Results

Conclusion