Maxillary sinus lift to enable one stage implant placement using Nanobone & PRF with or without simvastatin.

Abstract

Objective: Aim of this study was to evaluate the effect of using Nanobone & PRF with or without simvastatin on sinus lift and one stage implant placement. Material & Methods: 20 patients need sinus lift for implant placement in atrophied posterior maxilla were divided in two groups (group I: maxillary sinus left made by using synthetic bone substitute (NanoBone) & PRF Without simvastatin, while in group II using NanoBone & PRF with simvastatin. Results: Six months after surgery the mean of bone height gain in group I was 11.349 mm and the mean bone density was 297.8 Hounsfield units, while in group II the new bone height was 11.889 mm and the mean bone density was 314.3 Hounsfield units. During and after surgery there were no major complication and no implant failure. For endo sinus bone gain results were statistically significant in favour of group II (P<0.05). Conclusion: Both regenerative approaches showed significant improvements in clinical and radiographic results. However, adding simvastatin in combination with Nanobone & PRF showed better bone gain at 6 months in maxillary sinus lift and implant placement.