MAXILLARY METASTASIS OF BREAST CANCER

Abstract

Metastatic tumor in the oral cavity represents approximately 1% of all oral tumors and usually affects soft tissues or jawbones. A 45-year-old female sought an oral medicine service due to a painful well-defined ulcerated lesion with oroantral communication in the hard palate. The lesion measured 1.5 × 1.0cm and had a 21-day history. The patient reported headache, dysphagia, and left breast sectorectomy three years earlier for treating triple-negative breast cancer positive for BRCA2 mutation. The diagnostic hypotheses included metastatic lesion of breast adenocarcinoma, necrotizing sialometaplasia, and malignant salivary gland tumor. A partial biopsy was performed and the histopathological and immunohistochemistry analyses confirmed the mammary origin of the tumor. The patient was referred to the medical team for managing the recurrence of the disease. Further evaluation showed metastatic lesions in the skin, lungs, bones, liver and brain. Considering the disease was disseminated and uncontrolled, the patient was referred to palliative care. Metastatic tumor in the oral cavity represents approximately 1% of all oral tumors and usually affects soft tissues or jawbones. A 45-year-old female sought an oral medicine service due to a painful well-defined ulcerated lesion with oroantral communication in the hard palate. The lesion measured 1.5 × 1.0cm and had a 21-day history. The patient reported headache, dysphagia, and left breast sectorectomy three years earlier for treating triple-negative breast cancer positive for BRCA2 mutation. The diagnostic hypotheses included metastatic lesion of breast adenocarcinoma, necrotizing sialometaplasia, and malignant salivary gland tumor. A partial biopsy was performed and the histopathological and immunohistochemistry analyses confirmed the mammary origin of the tumor. The patient was referred to the medical team for managing the recurrence of the disease. Further evaluation showed metastatic lesions in the skin, lungs, bones, liver and brain. Considering the disease was disseminated and uncontrolled, the patient was referred to palliative care.