Abstract
A new oroidin dimer, mauritiamine (1), has been isolated from the marine sponge Agelas mauritiana along with the known oroidin (2) and 4,5-dibromopyrrole-2-carbamide (3). Their structures were determined by spectral analysis. Compounds 1 and 2 inhibited larval metamorphosis of the barnacle Balanus amphitrite with ED50 values of 15 and 19 μg/mL, respectively, while 3 promoted larval metamorphosis of the ascidian Ciona savignyi at a concentration of 2.5 μg/mL.
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