Abstract
Mature cystic teratomas, or dermoid tumors, are the most common benign ovarian neoplasms in young women. Malignant transformation is rare, and occurs in less than 2% of the cases. The heterogeneous histological composition of these tumors may be responsible for the occasional elevation of various tumor markers, such as Ca19-9 and Ca125. We describe one case of mature cystic teratoma in a 50-year old woman with the second highest level of Ca19-9 (8922.76 UI/mL) described in the literature. We concluded that abnormal levels of Ca19-9 are not necessarily associated with ovarian malignancy, and may lead to unnecessary medical intervention and patient anxiety. Therefore, the clinical features, imaging studies and antigen testing should be interpreted carefully, and should not limit the surgical approach.
Highlights
Mature cystic teratoma (MCT), or dermoid tumor, was described for the first time 300 years ago, and is the most common ovarian tumor in adolescents and young women.[1]
To the extent of our knowledge, we describe a case of MCT
Mature cystic teratomas are ovarian germ cell tumors believed to arise from the primordial germ cells by failure of meiosis II or from a pro-meiotic cell in which meiosis has failed
Summary
Mature cystic teratoma (MCT), or dermoid tumor, was described for the first time 300 years ago, and is the most common ovarian tumor in adolescents and young women.[1] It accounts for 10–25% of all ovarian neoplasms, and 60% of all benign ovarian tumors.[2,3] most women presenting MCT are asymptomatic, $ 20% can have complications such as torsion, rupture, infection and malignant transformation (0,17–3% of cases).[4,5] MCTs are composed of one or more of the three well differentiated tissues derived from the ectoderm, mesoderm and/or endoderm germ layers. To the extent of our knowledge, we describe a case of MCT with the second highest level of the serum Ca19–9 described in literature.[8]
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