Abstract

The field of computational biology has experienced a tremendous growth in the past 15 years. In this bibliography, we survey some of the most significant contributions that were made to the field and which employ mathematical programming techniques, while giving a broad overview of application areas of modern computational molecular biology. The areas include sequence analysis, microarrays, protein structure and function, haplotyping and evolutionary distances.

Highlights

  • Computational molecular biology, or, shortly, computational biology, is a research field which studies the solution of computational problems arising in molecular biology

  • In the very early years, computational biology was a topic of limited interest, because it was of limited practical impact

  • Many of the first computational biology papers were written by theoretical computer scientists and appeared in CS theory conferences

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Summary

Introduction

Computational molecular biology, or, shortly, computational biology, is a research field which studies the solution of computational problems arising in molecular biology. The former problem consists in trying to determine the 3D structure of a protein from its aminoacid sequence. This section contains an annotated bibliography of mathematical programming papers in computational biology, grouped by problem areas.

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