Abstract
Abstract The COVID-19 pandemic brought to light the need to rethink the ways in which rules and decisions are made and what rule-making can achieve under conditions of uncertainty. Among the recommendations put forward by a recent Manifesto is to ‘pay attention to the unknowns’. This forces us to examine three interrelated questions: what is the nature of mathematical modelling? What kinds of uncertainty are there in the contested arena of science for rule-making? What ideas and approaches can help us better address the interaction between mathematical modelling and rule-making under conditions of uncertainty? This chapter addresses these three questions in detail.
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