Mathematical modelling of clonorchiasis with human treatment and fish vaccination versus snail control

Abstract

Clonorchiasis is an important food-borne parasitic disease that has been largely understudied. We examine the dynamics of clonorchiasis with human treatment and fish vaccination versus snail control. Four mathematical models are proposed and analysed, both analytically and numerically. We show that fish vaccination is a valid method of control and derive the maximal period of molluscicide application in order to control the snail populations. It follows that a variety of methods may be necessary to control clonorchiasis.