Mathematical modeling of a new way of renal artery denervation

Abstract

The aim of the work is to create a new design of electrodes for renal denervation. In standard RFA systems, monopolar heating is most often used, by introducing an RF electrode inside the vessel. This approach leads to the need to interrupt blood flow during the procedure. In addition, the monopolar mode of operation requires the contact of the inserted electrode with the vessel walls, which greatly complicates the design of the electrode system. Point contact of the electrode system with the vessel can damage the inner walls of the artery. It is proposed to use a multi-electrode structure for external stimulation by creating a hollow cylindrical thermal field for effective treatment. It has been established that external heating will create the required thermal field without direct contact with the walls of the artery. The external arrangement of the electrodes makes it possible to regulate the temperature on the external surface of the vessel. With such heating, it is not necessary to block the blood flow, and due to the symmetry of the arrangement, continuous heating can be obtained without moving the electrodes during the procedure. Mathematical modeling confirms the possibility of vascular denervation during external heating.