Abstract
COVID-19 is a world pandemic that has affected and continues to affect the social lives of people. Due to its social and economic impact, different countries imposed preventive measures that are aimed at reducing the transmission of the disease. Such control measures include physical distancing, quarantine, hand-washing, travel and boarder restrictions, lockdown, and the use of hand sanitizers. Quarantine, out of the aforementioned control measures, is considered to be more stressful for people to manage. When people are stressed, their body immunity becomes weak, which leads to multiplying of coronavirus within the body. Therefore, a mathematical model consisting of six compartments, Susceptible-Exposed-Quarantine-Infectious-Hospitalized-Recovered (SEQIHR) was developed, aimed at showing the impact of stress on the transmission of COVID-19 disease. From the model formulated, the positivity, bounded region, existence, uniqueness of the solution, the model existence of free and endemic equilibrium points, and local and global stability were theoretically proved. The basic reproduction number (R0) was derived by using the next-generation matrix method, which shows that, when R0 < 1, the disease-free equilibrium is globally asymptotically stable whereas when R0 > 1 the endemic equilibrium is globally asymptotically stable. Moreover, the Partial Rank Correlation Coefficient (PRCC) method was used to study the correlation between model parameters and R0. Numerically, the SEQIHR model was solved by using the Rung-Kutta fourth-order method, while the least square method was used for parameter identifiability. Furthermore, graphical presentation revealed that when the mental health of an individual is good, the body immunity becomes strong and hence minimizes the infection. Conclusively, the control parameters have a significant impact in reducing the transmission of COVID-19.
Highlights
Coronavirus disease-2019 (COVID-19) is an infectious disease caused by a newly discovered coronavirus named severe acute respiratory syndrome coronavirus-2 (SARSCOV-2)
Stress affects many quarantined people whereby their immune system is disturbed by the COVID-19, and this is most likely because during quarantine, people are isolated from their families and community members, so they develop fear, and later, the body becomes stressed which affects their immune system
A mathematical model was developed for the transmission of COVID-19 when a human is stressed
Summary
Coronavirus disease-2019 (COVID-19) is an infectious disease caused by a newly discovered coronavirus named severe acute respiratory syndrome coronavirus-2 (SARSCOV-2). Khan et al [10] discussed on isolation and quarantine as the best ways of fighting COVID-19 disease. Ashcroft et al [15] discussed the impact of quarantine on the transmission of COVID-19 disease showing that many countries impose quarantine to ensure the exposed people and those from abroad are isolated for a specific period of time to prevent the spread of the disease. These measures took a larger economical toll and affected the health of the isolated individuals.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Computational and Mathematical Methods in Medicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
