Mathematical analysis of affinity hemodialysis on T-Cell depletion

Abstract

Investigation into the mathematical analysis of affinity hemodialysis on T-cell depletion is considered to give more significant understanding on the infection dynamics of HIV. Our model revealed the possibility of more than two infected equilibriums with the incorporation of recovery through the affinity hemodialysis. The conditions for stable infected equilibrium to prevent full-blown of AIDS are obtained and stated as hypothesis. This work has, therefore, open the way for partnerships among modelers and clinicians to strengthening the insight into the nature and process of viral multiphasic decay noticed in some treated patients. The initial growth of virus, infected cells and glycoprotein as well as possibility of total viral clearance are examined in the study.