Abstract
Background:Prenatal supplementation has been inversely associated with childhood, but not with infant, leukaemia.Methods:Mothers of 443 cases of infant leukaemia diagnosed during 1996–2006 and 324 frequency-matched controls completed interviews. Associations were evaluated by unconditional logistic regression.Results:We observed no associations between prenatal vitamin (odds ratio (OR)=0.79, 95% confidence interval (CI): 0.44–1.42) or iron supplementation (OR=1.07, 95% CI: 0.75–1.52) and infant leukaemia after adjustment for race/ethnicity and income. Similar results were observed for leukaemia subtypes analysed separately.ConclusionThe observed null associations may be attributable to high supplementation rates and/or national fortification programmes.
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