Abstract
Introduction: Sever sepsis and septic shock contributes to maternal morbidity and mortality. The etiology of sever sepsis and septic shock during pregnancy and postpartum result from obstetric related or non-obstetric related conditions. Objectives: It aimed to determine rate, characters, morbidity and mortality of septic obstetric cases at Omdurman New Hospital. Methods: It was a descriptive, prospective, analytic, cross-sectional hospital based total coverage study; conducted at Omdurman New Hospital (ONH), Khartoum-Sudan. Results: Sever sepsis and septic shock rate 1.16 (13/1124 = 1.16%) of hospital pregnancy complication admission. Hyperthermia, Tachycardia and hypotension are the main presenting clinical findings and uterine infection is the main focus of sepsis. The mean average Intensive Care Unit (ICU) stay is 6.3-day. Organs dysfunctions are the main morbidity and mortality is reported in five cases. Conclusion: Sever sepsis and septic shock contributes in maternal morbidity and mortality. Safe obstetric care prevents maternal sepsis and improves the outcome. Management of sever sepsis and septic shock remains a challenge in obstetric medicine.
Highlights
Sever sepsis and septic shock contributes to maternal morbidity and mortality
During a consensus conference conducted by the Society of Critical Care Medicine in 1992, the systemic inflammatory response syndrome (SIRS) was defined as a disseminated organic inflammatory response to various types of insult characterized by the presence of at least two of the following criteria: fever or hypothermia, tachycardia, tachypnea, and leukocytosis or leukopenia
During study period the hospital admission was 1124 cases from pregnancy complications; 142 cases were admitted at Intensive care unit (ICU) 13 cases were of severe sepsis and septic shock, made the rate 1.16 (13/1124 = 1.16%)
Summary
Sever sepsis and septic shock contributes to maternal morbidity and mortality. During a consensus conference conducted by the Society of Critical Care Medicine in 1992, the systemic inflammatory response syndrome (SIRS) was defined as a disseminated organic inflammatory response to various types of insult characterized by the presence of at least two of the following criteria: fever or hypothermia (body temperature >38 ̊C or 90 bpm), tachypnea (respiratory rate >20 breaths per minute or arterial carbon dioxide tension—PaCO2 < 32 mmHg), and leukocytosis or leukopenia (white blood cell count >12,000/mm or 10% of immature forms). Sepsis was defined as SIRS associated with the presence of an infection source Those definitions were established based on non-pregnant individuals [1]. They guide admission to Intensive Care Unit (ICU) and treatment as well to predict mortality and serious morbidity
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