Abstract
(BJOG. 2022;129:2082–2093) Pre-eclampsia is a complication affecting 2% to 4% of pregnancies and is associated with a high rate of maternal and infant mortality. The risk of developing pre-eclampsia is related to age, weight, race, method of conception, personal and family history, and pre-existing conditions. Studies from predominantly white countries have indicated that some minority groups have an increased incidence of pre-eclampsia, and other minority groups have decreased or similar incidence to white women. These studies, however, have mostly observed relative incidence without correcting for confounding variables in maternal characteristics and medical history. This study aimed to examine associations between race and pre-eclampsia after adjusting for confounding factors of demographics and medical history, and to present a systematic review and meta-analysis of information on this topic.
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