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Abstract
EUROPEAN JOURNAL OF PSYCHO- TRAUMATOLOGY Supplement 1, 2012 Effects of Traumatic Stress Molecular and Hormonal Mechanism Abstracts from 42 nd Annual Conference New York, September 11–14, 2012
Highlights
Rationale/ statement of the problem: Increasing evidence suggests exposure to adverse conditions in intrauterine life may increase the risk of developing attention-deficit/hyperactivity disorder (ADHD) in childhood
Maternal pre-pregnancy body mass index (BMI) was a significant predictor of child ADHD symptoms (F(1,158) 04.80, p 0 0.03) and of child performance on the Go/No-go Task (F(1,157) 08.37, p 00.004) after controlling for key potential confounding variables
A test of the mediation model revealed that the association between higher maternal pre-pregnancy BMI and child ADHD symptoms was mediated by impaired executive function (inefficient/less attentive processing; Sobel test: t02.39 (90.002, SEM); p 00.02)
Summary
Rationale/ statement of the problem: Increasing evidence suggests exposure to adverse conditions in intrauterine life may increase the risk of developing attention-deficit/hyperactivity disorder (ADHD) in childhood. Title Maternal pre-pregnancy obesity and child ADHD symptoms, executive function and cortical thickness Effects of Traumatic Stress Molecular and Hormonal Mechanism
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