Abstract

Abstract Measurements of serum volume, total body water, urinary estriol, intravascular protein and albumin masses, red cell volume and serum heat-stable alkaline phosphatase revealed differences between primigravid and multigravid singleton and twin pregnancies. There were no such differences in serum sodium, potassium, chloride, osmolarity or urea. There is a relationship between serum volume and birth weight in both primigravid and multigravid singleton and multigravid twin pregnancies. On the other hand there is a greater expansion of total body water and a relationship with baby weights in first pregnancies only, both singleton and twin, compared with subsequent pregnancies.

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