Abstract
Background: Major depression is one of the most common psychiatric disorders, often present together with anxiety, and affects 1 in 4 women worldwide. Depression has an even higher prevalence during pregnancy, affecting 10-20% of pregnant women, and has been associated with preterm delivery and may later impact the child’s development. In the present study we aimed to identify changes in DNA methylation of the cellular immune system as a possible biological marker of maternal mood and anxiety disorders and their effects on the child’s development.
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