Abstract
Background: Pregnant ladies are most likely to develop relative iodine deficiency during pregnancy to affect thyroid function in our population unless specific dietary care or therapeutic iodine supplementation is taken into account which is yet to be materialized. Methods: In this cohort study sixty uncomplicated normal pregnant women were enrolled in 1st trimester and followed up till delivery. In every trimester maternal iodine status & thyroid status were determined by urinary iodine & serum thyroid hormone concentration respectively. Results: Women progressively become more iodine deficient & tends to be hypothyroid as pregnancy advances. At 3rd trimester of pregnancy maternal Urinary Iodine found to be negatively correlated with their serum TSH. Conclusion: During pregnancy women develop iodine deficiency which adversely affects the thyroid function. So adequate iodine monitoring and iodine nutrition during pregnancy is necessary. Keywords: Urinary iodine level, TSH, FT3, FT4. doi: 10.3329/jom.v10i2.2815 J MEDICINE 2009; 10 : 56-59
Highlights
Thyroid status is known to have an important bearing on the ability of women to conceive and to bring a normal infant to term
Our people get iodine mainly from iodized salt provided by nationwide salt iodization program
This study has been designed to explore the iodine status & thyroid status of Bangladeshi pregnant women used to conventional dietary practice during pregnancy
Summary
Thyroid status is known to have an important bearing on the ability of women to conceive and to bring a normal infant to term. Both maternal hyper and hypothyroidism have deleterious effect on pregnancy out come and thyroid hormone excess has direct toxic effect on fetus.[1,2]. Very few longitudinal studies abroad but none in our country have considered the maternal thyroid function during the course of pregnancy in relation to maternal iodine status. This study has been designed to explore the iodine status & thyroid status of Bangladeshi pregnant women used to conventional dietary practice during pregnancy. Pregnant ladies are most likely to develop relative iodine deficiency during pregnancy to affect thyroid function in our population unless specific dietary care or therapeutic iodine supplementation is taken into account which is yet to be materialized
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