Abstract
Premature closure of ductus arteriosus (PCDA), defined as early constriction and closure of fetal ductus arteriosus, is induced by a certain class of anti-inflammatory agents (cyclooxygenase inhibitors), which inhibit prostaglandin synthesis..
Highlights
Premature closure of ductus arteriosus (PCDA), defined as early constriction and closure of fetal ductus arteriosus, is induced by a certain class of anti-inflammatory agents, which inhibit prostaglandin synthesis
Fetal echocardiography revealed absent ductus arteriosus flow and tricuspid regurgitation
The present case of PCDA was possibly associated with maternal daily intake of polyphenol-rich dark chocolate after 34 weeks
Summary
Premature closure of ductus arteriosus (PCDA), defined as early constriction and closure of fetal ductus arteriosus, is induced by a certain class of anti-inflammatory agents (cyclooxygenase inhibitors), which inhibit prostaglandin synthesis. Premature closure of ductus arteriosus (PCDA) is known to be induced by antiinflammatory agents including polyphenols. We report a case of PCDA potentially associated with maternal daily intake of polyphenol-rich dark chocolate in late gestation. Fetal echocardiography revealed absent ductus arteriosus flow and tricuspid regurgitation.
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