Abstract

Maternal carriage of extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E), such as Escherichia coli and Klebsiella pneumoniae, can cause adverse sequelae during pregnancy. E. coli is the second most frequent cause of neonatal sepsis after Group B Streptococcus (GBS) and the most frequent cause in preterm infants. Preterm E. coli isolates have higher rates of ESBL-E phenotype. Clinical guidelines for antibiotic treatment during labor in maternal GBS colonization exist but no guidelines are available for maternal carriage of ESBL-E.

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