Maternal and neonatal outcomes in pregnant women with COVID-19 in a tertiary care hospital

Abstract

Background: The first case of the new Corona virus was identified in Wuhan, China in December 2019 and since then it spread around the world to other countries. The World health Organisation declared that the CoV-19 pandemic as a public health emergency of international concern (PHEIC) on 30 Jan 2020. In our hospital we managed Covid-19 positive patients as per guidelines. Here we are presenting the data of management and clinical outcomes of COVID-19 positive pregnant patients in our institution.Materials & Methodology: In this study we retrospectively reviewed the medical records of all COVID-19 positive pregnant women who were admitted to PESIMSR from January 2021 to August 2021, after obtaining permission from the institute. The infection status was determined via real-time polymerase chain reaction (RT-PCR) of nasopharyngeal swab specimen. In a pre-constructed data form the details regarding obstetric data, clinical status, symptoms, maternal and fetal outcomes were noted. Patients treated in an outpatient setting were not included.Results: 125 COVID-19 positive pregnant women were admitted in our hospital during study period. Mean maternal age was 23.9+_4.2 years. The mean gestational age calculated was 37.5±1.5 weeks. Cesare an section was performed in 33.6% of cases and 65.6% cases delivered vaginally. Most of the cases were asymptomatic. Patients with mild disease, without acute respiratory distress syndrome (ARDS), responded well to the supportive treatment. 10 babies required the admission in the new born intensive care unit and were discharged. All neonates tested negative for COVID-19, which showed no evidence of vertical transmission of COVID-19 in study group. Neither maternal nor neonatal deaths occurred.Conclusion: Our data showed that the course of Corona virus disease, COVID -19 in pregnancy is mild in the majority of cases and neonatal outcomes also appeared favourable.