Abstract
Hemostasis is a dynamic process that begins at early stages of fetal development. The hemostatic system comprises procoagulant, natural anticoagulant, and fibrinolytic proteins that interact with each other, as well as with the endothelial wall and blood cells in a complex, yet balanced manner, aiming to avoid either bleeding or thrombosis. Pregnancy is a unique physiological state in which natural biologic alterations predispose both mothers and their offspring to higher risk of hypercoagulability and bleeding. This special issue of Seminars in Thrombosis and Hemostasis is dedicated to maternal and neonatal hemostasis.
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