MATERNAL AND FETAL OUTCOMES OF JAUNDICE DURING A COMPLICATED PREGNANCY IN TERTIARY CARE HOSPITAL IN KAKINADA DISTRICT: A PROSPECTIVE OBSERVATIONAL STUDY

Abstract

Background: Viral hepatitis is one of the most common and potentially serious infections that can occur in pregnant women. Liver disease in pregnancy, although rare, can seriously affect the mother and fetus. Physiological changes of a normal pregnancy can be confounding with the sign and symptoms of liver diseases. But it is an essential medical disorder because it has adverse effects on the mother and fetus like PPH, preterm labour, IUD, fetal distress, etc. This study aims to analyze the incidence, demographics, obstetric prole, and causes of jaundice in pregnancy and to know the maternal and fetal outcomes. This is an observational Materials And Methods: study conducted by the Department of Obstetrics and Gynaecology, Governments General Hospital (tertiary care hospital) Kakinada, East Godavari District, Andhra Pradesh. 54 antenatal patients with clinical/laboratory evidence of jaundice were selected for the study between January 2020 to December 2020. Results: The mean (Standard deviation) age of patients was 25.5 ± 5.4. 54 patients had jaundice during pregnancy were analysed. 77% of the patients were between 21 and 35 years old. Most cases were Primi gravida. The incidence of jaundice was 3.7%. The most common cause of jaundice was hemolysis, elevated liver enzymes, and low platelets (HELLP). The most common maternal complication was disseminated intravascular coagulation. The maternal mortality rate was eight. The majority of perinatal outcomes were preterm births. Jaundice in pregnancy has Conclusions: adverse feto-maternal consequences. Improving health awareness, education, regular prenatal examinations, and early referrals lead to early diagnosis and treatment of jaundice during pregnancy, thereby reducing maternal and fetal mortality and morbidity.