Abstract

SummaryGeneral anaesthesia in patients with known mastocytosis can be extremely hazardous. Massive histamine release may be triggered by drugs or by the psychological and environmental stresses associated with surgery and can result in significant cardiovascular collapse, respiratory compromise and even death. We present a case of anaphylaxis following induction of anaesthesia in a patient whose diagnosis of mastocytosis was not disclosed during pre‐assessment for emergency surgery. We believe it is the only case reported where the patient has survived their hospital admission in such circumstances despite significant and prolonged cardiovascular compromise.

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