Abstract

Master–Slave-Type Gait Training System for Hip Movement Disorders

Highlights

  • The myelin sheath formed by Schwann cells (SCs) to wrap an axon is critical in increasing the action-potential conduction velocity (CV)

  • Few cells appeared in the nonpatterned area (

  • We developed a neuron/SC coculture device by combining the stripe pattern with the microtunnel on an microelectrode array (MEA) substrate

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Summary

Introduction

The myelin sheath formed by Schwann cells (SCs) to wrap an axon is critical in increasing the action-potential conduction velocity (CV). Sensors and Materials, Vol 30, No 12 (2018) This in vivo recording method enables us to record a summated response generated by electrical stimulations in multiple axons, providing the average CV in the bulk population. The average CV reliably reflects the CV in the fully mature population, this method is inapplicable to the evaluation of the maturation process. The invasiveness of in vivo recording is a challenge for the continuous recording of neuronal activities during myelin maturation. Owing to these difficulties, the sequential changes in the CV during myelin maturation are unclear. A method that enables continuous evaluation of the CV of individual axons during myelin maturation is required

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