Abstract

Mast cells are normally found in the lungs of most experimental animals, occupying the interstitial space and sparsely distributed. Their normal morphology at the ultrastructural level is one of uniformity in their granular inclusions, cytoplasmic extensions into fingerlike projections, and a large central nucleus. Mitochondria are relatively few when compared with highly active cells such as those in the liver. These cells produce a histamine-heparin-protein complex when granule release takes place.

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