Abstract
In vivo and in vitro experiments show that sickle trait blood can be safely used for blood transfusions. However, nowhere in the literature is there a reference as to the possible dangers of the use of such blood in exchange transfusions.We are reporting a case of a premature white infant with physiological jaundice who received an exchange transfusion of blood containing hemoglobin A and S and expired five days later. Autopsy revealed generalized intravascular aggregation of sickled erythrocytes similar to that found in patients dying in sickling crises.
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