Abstract
IntroductionGastritis Cystica Profunda is a well recognized entity which may occur several years after previous gastric surgery. This is a premalignant condition and may lead on to carcinoma of the stomach.Case presentationWe report a case of a 50-year-old man with epigastric pain and haematemesis. 28 years ago he had undergone partial gastrectomy and gastroenterostomy for benign gastric ulcer. An Upper gastrointestinal endoscopy showed a possible bleeding vessel on the anterior wall lesser curve of the stomach. The lesion was injected with adrenaline 1 in 100,000. In spite of the intervention he continued to have haemetemesis with significant haemodynamic impairment. At exploratory laparotomy, an oedematous ridge on the posterior wall with a bleeding point on the posterior gastric wall. Histology showed features consistent with gastritis cystica profunda. He made an excellent post-operative recovery.ConclusionWe suggest that patients who are diagnosed with gastritis cystica profunda should be regularly followed up as this is a premalignant condition.
Highlights
Gastritis Cystica Profunda is a well recognized entity which may occur several years after previous gastric surgery
We suggest that patients who are diagnosed with gastritis cystica profunda should be regularly followed up as this is a premalignant condition
Gastritis cystica profunda has been described in a patient with a history of gastric ulcer that was treated with H2 blockers [5]
Summary
Gastritis Cystica Profunda is a well recognized entity occurring several years after previous gastric surgery [1]. Disruption of integrity of muscularis mucosa causes the migration of epithelial contents into the sub mucosa with subsequent atrophic gastritis, intestinal metaplasia and cystic dilatation of gastric glands [2]. This is a precursor of cancer of the stomach [1]. Gastritis cystica profunda has been described in a patient with a history of gastric ulcer that was treated with H2 blockers [5] This indicates that GCP can occur after exposure of gastric mucosa to chronic mucosal inflammation, which subsequently leads to hyperplastic and metaplastic changes and increased risk for progression towards carcinoma. Stage 2: with gastric glands spreading into the sub mucosa (gastritis cystica profunda)
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