Abstract
We analysed human serine racemase for the first time from human foetal brain by mass spectrometrical methods, MALDI MS and MS/MS. The detection of human serine racemase from a transient area of human foetal brain, the perireticular nucleus, that is suggested to be mainly involved in guidance of corticofugal and thalamocortical fibers, may be a clue for the important role of this enzyme in neuronal migration and brain development via regulation of NMDA receptor activity.
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