Masked Hypertension is Common in Patients with a Hypertensive Response to Exercise and may Help to Explain Increased Cardiovascular Risk in this Population

Abstract

107 Masked Hypertension is Common in Patients with a Hypertensive Response to Exercise and may Help to Explain Increased Cardiovascular Risk in this Population James L. Hare ∗, James Sharman, Scott Thomas, Rodel Leano, Thomas H. Marwick University of Queensland, Brisbane, Australia Background:Ahypertensive response to exercise (HRE) is defined as normal clinic blood pressure (BP) and exercise BP> 210/105mmHg (men) or >190/105mmHg (women). Several studies have shown that a HRE predicts onset hypertension and adverse cardiovascular cardiac risk, but the mechanisms of this association remain unclear. None of these studies have measured 24h ambulatory BP monitoring (ABPM), which may help to explain increased risk, and was the aim of this study. Methods: We prospectively identified 57 untreated patients with a HRE (age 55± 8 years, 61% male) free from coronary artery disease. All patients underwent 24 h ABPM with comprehensive clinical and echocardiographic evaluation, including tissue Doppler imaging (strain and strain rate) in 52patients. Patientsweredefined as having masked hypertension if 24 h systolic BP (SBP) was ≥130mmHg and clinic BP< 140/90mmHg. Results: Sixty five percent of the population had masked hypertension and the remaining were normotensive. P h b ( a C b b i