Abstract
Tumors of the ovary that cause symptoms related to the endocrine system include arrhenoblastoma, masculinovoblastoma, often called the adrenal rest tumor, and luteinized tumors, variously called luteomas, luteinomas, and luteinized granulosa cell or theca cell tumors. The two that result in symptoms of masculinization are arrhenoblastoma and masculinovoblastoma. Arrhenoblastomas are somewhat commoner, 94 having been reported in 1947 by Iverson.1Masculinovoblastomas are rarer. Iverson limited the reported cases to 15 definitely established, after excluding six cases in which the patients did not have complete masculinization associated with a lipoid cell tumor of the ovary. The origin of lipoid cell tumors is disputed, some authors believing that they arise from adrenal rests and some believing that they arise from undifferentiated cells in the ovary, while still others believe that both modes of origin are possible. Histologically, these tumors resemble adrenal cortical tissue. According to Curtis,2this group of tumors
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