MARKET ANALYSIS OF SEMISOLID DOSAGE FORMS REGISTERED IN UKRAINE AND RESEARCH OF EXCIPIENTS INCLUDED TO THEIR FORMULAS

В V Vons ,М Б Чубка ,Т А Грошовый

doi:10.11603/2312-0967.2015.1.3766

Abstract

<span class="a"><span lang="EN-US">it has been investigated the domestic market of semisolid dosage forms registered in Ukraine. Excipients as a part of various semisolid dosage forms have been studied. It has been found that semisolid dosage forms include basic substrate, emulsifiers, gelling agents, solvents, antimicrobial preservatives, antioxidants, solubilizers, colorants, flavors, stabilizers pH and thickeners.</span></span>

Highlights

Nowadays, semisolid dosage forms (SDF) take the fifth range among the other dosage forms that are registered in Ukraine [1] as well as the main position among medications (M) of local therapy for treatment of dermatological diseases [2]
After analyzing the list of medications approved in Ukraine, which are available without prescription from pharmacies and their departments, agreed by the order of Ministry of Health of Ukraine No 166 dated on 26.02.2013, a group of authors has found that the SDF cover about 12% of all medications, including 58 % of semisolid medication (SM) could be sold without prescription [2]
SDF are divided into gels, pastes, liniments, creams, ointments according to the order of Ministry of Health of Ukraine No 235 dated on 26.06.2002, the Classification of medications [4]

Summary

Introduction

Semisolid dosage forms (SDF) take the fifth range among the other dosage forms that are registered in Ukraine [1] as well as the main position among medications (M) of local therapy for treatment of dermatological diseases [2]. SDF are divided into gels, pastes, liniments, creams, ointments according to the order of Ministry of Health of Ukraine No 235 dated on 26.06.2002, the Classification of medications [4]. The list of excipients (E) that can be used for the production of medications in Ukraine is regulated by the Ministry of Health of Ukraine by the order dated on 19.06.2007, No.339 and includes 38 586 excipients (E) and colorants [6].

Results

Conclusion