Abstract
Recent data showed that some bone related markers correlate with BMI in the pediatric population. Moreover, obesity in childhood increase the risk of atherosclerosis development by induced oxidative stress. The aim of this study was to determine the relationship between bone turnover markers, nutritional status and oxidative stress in obese children comparing to the lean controls. Bone turnover markers (osteocalcin (OC), N-terminal telopeptide of type I collagen (NTx), sRANKL), oxidative stress markers (TAC – total antioxidative capacity, glutathione peroxidase, oxy-LDL) and leptin were determined in 50 obese and 79 healthy children. BMI and body composition (fat mass (FAT), fat-free mass (FMM), predicted muscle mass (PMM) and total body water (TBW)) were evaluated in all children. OC was significantly lower in obese children and correlated significantly (negatively p
Published Version
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