Abstract
Markers for the Characterization of Liver Mesenchymal Stem Cell
Highlights
Mesenchymal stem cells (MSCs) have the characteristics of self-renewal, immune regulation and multipotency
Scientists have isolated liver mesenchymal stem cells (LMSCs) from different species and attempted to characterize them in hopes that these cells could be a better alternative to bone marrow mesenchymal stem cells (BMSCs), especially for liver diseases [8]
The International Society of Cell Therapy (ISCT) states that cultured human BMSCs are positive for expression of CD105, CD73, and CD90 and negative for expression of CD11b or CD14, CD19 or CD79a, CD34, CD45, and HLA-DR (11)
Summary
Mesenchymal stem cells (MSCs) have the characteristics of self-renewal, immune regulation and multipotency. MSCs were first described as stromal stem cells from the bone marrow that have a spindle shape in culture. Scientists have isolated liver mesenchymal stem cells (LMSCs) from different species and attempted to characterize them in hopes that these cells could be a better alternative to bone marrow mesenchymal stem cells (BMSCs), especially for liver diseases [8].
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