Abstract

The Ocean, called the ‘mother of origin of life’, is a rich source of biological and chemical diversity. Marine floras include microflora (bacteria, actinobacteria, cyanobacteria and fungi), microalgae, macroalgae (seaweeds), and flowering plants (mangroves and other halophytes). Marine organisms have unique properties as they are exposed to extreme marine environmental conditions. This vast marine floral resource offer a great way for discovery of new drugs which can fight deadly diseases like cancer, acquired immune deficiency syndrome (AIDS), arthritis, etc. Sea has got plenty of metabolites and other resources in living or dead form. Thermo-stable proteases, lipases, esterases, and starch and xylan degrading enzymes have been actively sought from bacterial and archaeal hyperthermophilic marine microorganisms. Marine cyanobacteria appear to be potential sources for production of vitamins such as B complex group and vitamin-E. The carotenoids and phycobiliprotein pigments of cyanobacteria have commercial value as natural food colouring agents, as feed additives, as enhancers of the color of egg yolks, to improve the health and fertility of cattle, as drugs and in the cosmetic industries. Some anti-HIV activity has been observed with the compounds extracted from Lyngbya lagerhaimanii and Phormidium tenue. Thus an attempt to review few marine derived biomedical resources was done emphasizing that with the advent of modern technologies it is anticipated that the marine environment will become an invaluable source of novel compounds in the future.

Highlights

  • More than 30 000 diseases have been clinically described, less than one-third of these can be treated symptomatically and only a few can be cured

  • Bioactive compounds derived from marine organisms has been reviewed in results

  • Still there is a lot to unravel regarding the richness of marine environment

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Summary

Introduction

More than 30 000 diseases have been clinically described, less than one-third of these can be treated symptomatically and only a few can be cured. New therapeutic agents are urgently needed to treat medical needs that are currently unmet. Natural products once played a major role in drug discovery [1, 2]. The marine environment covers more than 70% of the world’s surface. In Ocean Habitats, there are two major marine provinces: the benthic (bottom) and the pelagic (water column). The benthic environment is divided by depth into the: Intertidal zone, Sublittoral zone, Bathyal zone, Abyssal zone, and the Hadal zone. The pelagic environment is divided into the Neritic Zone and the Oceanic Zone

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