Abstract

Abstract: Marine microorganisms are an important source of active natural products and drugs, which have become a research hotspot in recent decades. Due to the special marine ecological environment, the metabolic pathways of marine organisms have certain characteristics, and their metabolites are novel in structures and unique in activities. Xanthones and benzophenones are widely distributed in nature, and most of them are found in fungi and higher plants. They are described as "dominant structures" in the field of modern medicine because of their obvious pharmacological activities, including antibacterial and antifungal activities. This paper reviews the research progress of isolated microbial xanthone and benzophenone compounds from marine sources at home and abroad in recent years, including their chemical synthesis and biosynthesis, which lays a foundation for future utilization and development.

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