Abstract

Marijuana is the most common drug of abuse in the United States. Marijuana has more than 460 active chemical compounds including δ-9- tetrahydrocannabinol (THC). It acts via the CB1 and CB2 receptors that are distributed in various tissues in the body. Marijuana is known to cause tachycardia, bradycardia, hypertension, to decrease time angina, myocardial infarction and cardiac arrest. Till date, four cases of myocarditis/perimyocarditis associated with marijuana use have been reported. In one such case, it led to the development of heart failure in a young male patient. It is not clear if marijuana in and of itself causes myocarditis/perimyocarditis or if the etio-pathogenesis is actually related to the contaminants in marijuana such as pesticides and heavy metals. We hereby present a young male who with myocarditis related to marijuana use. Clinicians should have suspicion for myocarditis or perimyocarditis in patients presenting with chest pain following marijuana use.

Highlights

  • In 2016, over 26 million americans reported marijuana use within the last month [1]

  • Tachycardia, arrhythmias, hypotension, hypertension, and increase risk of myocardial infarction are adverse cardiovascular effects reported with marijuana use [6]

  • Four cases of myocarditis/perimyocarditis associated with marijuana use have been reported [8,9,10,11]

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Summary

Introduction

In 2016, over 26 million americans reported marijuana use within the last month [1]. Marijuana is the most commonly used drug of abuse in the United States [2]. Over 460 chemicals including δ-9- tetrahydrocannabinol (THC) have been reported in marijuana [5]. Tachycardia, arrhythmias, hypotension, hypertension, and increase risk of myocardial infarction are adverse cardiovascular effects reported with marijuana use [6]. Potency of marijuana is highly variable and it is often contaminated. Such contamination has little monitoring and is a public health concern [7]. Four cases of myocarditis/perimyocarditis associated with marijuana use have been reported [8,9,10,11]. To the best of our knowledge, we hereby present the fifth case

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