Abstract
The marijuana plant contains in excess of 400 chemical entities, of which 60 or more are cannabinoids (1). Delta-9-tetrahydrocannabinol (THC) is the major psychoactive cannabinoid in marijuana and has been shown to induce immunosuppressive effects both in vivo and in vitro. The drug inhibits lymphocyte responsiveness to mitogens and particulate antigens (2), decreases T-cell rosette formation (3,4), suppresses leukocyte migration (5), and alters macrophage morphology, function, motility, and protein expression (6–8).KeywordsSpleen MassMurine L929 CellInfected L929 CellCell Surface BlebCytoplasmic PolarizationThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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