Abstract
Marfan syndrome is a heritable disorder of connective tissue that can affect the heart, blood vessels, lungs, eyes, bones and ligaments. It is characterized by tall stature, elongated extremities, scoliosis and a protruded or caved-in breastbone. Patients typically have a long, narrow face. A high-arched palate produced by a narrow maxilla and skeletal Class II malocclusion due to mandibular retrognathia are other common features. For a patient with no family history of this disorder, at least three body systems must be affected before a diagnosis can be made—skeletal, cardiovascular and occular. Individuals affected by the syndrome routinely demand orthodontic treatment to correct the orofacial manifestations. This case report presents two patients who reported to the department of orthodontics with a chief complaint of protruding upper anteriors, but on thorough clinical examination and investigation were diagnosed as Marfan syndrome. A brief overview of the challenges involved in treating such patients is discussed herewith.
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