Mapping the topology of functional neural networks with single cell resolution

Abstract

Event Abstract Back to Event Mapping the topology of functional neural networks with single cell resolution Gabriel A. Silva1* 1 University of California San Diego, Bioengineering and Ophthalmology and Neurosciences Program, United States Understanding how neural circuits and networks represent, store, and process information is a central pursuit in neuroscience. It is anticipated that this will directly contribute to the understanding of higher order cognitive processes and provide a fundamental understanding of the central nervous system in both health and disease. One of the principle pursuits towards these aims is the reverse engineering of how neural circuits and networks function, in order to ultimately understand their dynamic properties. Our lab in particular is interested in how stereotypical cellular processes that underlie functional dynamic signaling in neural circuits scale and give rise to the information rich content and resultant properties of biological neural networks. We approach this by combining mathematical and computational modeling and nanotechnology with cellular neurobiology and imaging, specifically using real time dynamic fluorescence calcium imaging as an indicator and measure of function in both neuronal and glial networks. This talk will present some of our on-going theoretical, engineering, and experimental efforts aimed at identifying and mapping the functional connectivity topology of neural circuits and networks with single cell and sub-cellular resolution. Keywords: neuroengineering Conference: The Monte Verita' Workshop on the Frontiers in Neuroengineering, Ascona, Switzerland, 5 Sep - 9 Sep, 2010. Presentation Type: Oral Presentation Topic: Frontiers in Neuroengineering Citation: Silva GA (2010). Mapping the topology of functional neural networks with single cell resolution. Front. Neuroeng. Conference Abstract: The Monte Verita' Workshop on the Frontiers in Neuroengineering. doi: 10.3389/conf.fneng.2010.10.00022 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 17 Aug 2010; Published Online: 10 Sep 2010. * Correspondence: Prof. Gabriel A Silva, University of California San Diego, Bioengineering and Ophthalmology and Neurosciences Program, San Diego, United States, gsilva@ucsd.edu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Gabriel A Silva Google Gabriel A Silva Google Scholar Gabriel A Silva PubMed Gabriel A Silva Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.