Abstract
BackgroundTo explore the research trends for uveal melanoma with bibliometric methods using Web of Science Core Collection (WoSCC) and PubMed (PM).MethodsTo find UM-related studies, “uveal melanoma” was used as search term in the WoSCC and PM for the period time from 2000 to 2020. Bibliographic coupling analysis was used to investigate the journals with the highest number of UM-related publications. VOSviewer (VV) was used for mapping the knowledge domain and visualizing the co-occurrence of terms, authors, organizations, countries, co-citation literature, and keywords. The knowledge map based on WoSCC and PM was compared.ResultsIn the WoSCC 3,748 articles were found, while in PM the search resulted in 3,403 articles. The number of original articles has steadily grown in general in the past two decades. The top ten authors were contributing to 23% (n = 856) of all publications, while the top 10 institutions published 41% (n = 1524) of all articles. The top 3 journals with the highest number of publications for UM-related research included Investigative ophthalmology & visual science, Ophthalmology, and British Journal of Ophthalmology. Co-occurrence analysis based on author keywords showed 6 clusters. The most frequent keywords included are metastasis, prognosis, and brachytherapy. The latest research hotspots focused on BAP1, immunotherapy and GNAQ.ConclusionsGenetics and immunology are the latest research frontiers in uveal melanoma. There is a clear need for interdisciplinary, molecular and clinical research approaches to improve the fatal prognosis of uveal melanoma patients.
Highlights
To explore the research trends for uveal melanoma with bibliometric methods using Web of Science Core Collection (WoSCC) and PubMed (PM)
The latest research hotspots focused on BAP1, immunotherapy and GNAQ
There is a clear need for interdisciplinary, molecular and clinical research approaches to improve the fatal prognosis of uveal melanoma patients
Summary
To explore the research trends for uveal melanoma with bibliometric methods using Web of Science Core Collection (WoSCC) and PubMed (PM). Methods To find UM-related studies, ‘‘uveal melanoma’’ was used as search term in the WoSCC and PM for the period time from 2000 to 2020. The knowledge map based on WoSCC and PM was compared. Uveal melanoma (UM) is a common primary intraocular malignancy in Caucasians [1]. 85% of ocular melanomas are UM [2] This common malignant tumor has a poor prognosis and low survival rate. Compared to common ophthalmic diseases, the number of studies and research on UM is limited. Despite the relatively limited number of articles regarding UM research, researchers cannot read all of the UM literature, and abstracts, as a traditional type of literature, do not provide us with information on hot topics and current trends in the field of UM research
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