Abstract

Opinion polls on vaccine uptake clearly show that Covid-19 vaccine hesitancy is increasing worldwide. Thus, reaching herd immunity not only depends on the efficacy of the vaccine itself, but also on overcoming this hesitancy of uptake in the population. In this study, we revealed the determinants regarding vaccination directly from people’s opinions on Twitter, based on the framework of the 6As taxonomy. Covid-19 vaccine acceptance depends mostly on the characteristics of new vaccines (i.e. their safety, side effects, effectiveness, etc.), and the national vaccination strategy (i.e. immunization schedules, quantities of vaccination points and their localization, etc.), which should focus on increasing citizens’ awareness, among various other factors. The results of this study point to areas for potentially improving mass campaigns of Covid-19 immunization to increase vaccine uptake and its coverage and also provide insight into possible directions of future research.

Highlights

  • IntroductionMass vaccination is the only way to contain the spread of the SARS-CoV-2 virus, the cause of the Covid-19 pandemic

  • According to current knowledge, mass vaccination is the only way to contain the spread of the SARS-CoV-2 virus, the cause of the Covid-19 pandemic

  • A set of 33 topics was extracted from the large text dataset representing tweets on the topic of the Covid-19 vaccination

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Summary

Introduction

Mass vaccination is the only way to contain the spread of the SARS-CoV-2 virus, the cause of the Covid-19 pandemic. To bring this pandemic to an end, a large proportion of the world needs to be immune to the SARS-CoV-2 virus. To achieve herd immunity and cut the transmission chain, using a vaccine with a claimed 95% efficacy, we need to vaccinate at least 63% to 76% of the population [7] This required vaccine coverage is certainly very high, and may not be attained for many reasons. This is a huge challenge for pharmaceutical companies and finite healthcare resources, and for government agencies and regulatory authorities [8], [9], [31]

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