Abstract
Understanding the neural mechanisms underlying the regulation of eating behavior plays the leading role in assessment of food intake in normal individuals and in patients with obesity. Modern neuroimaging methods, such as functional MRI (fMRI), may shed the light on these mechanisms. A simple and reproducible visual fMRI-paradigm was developed for the assessment of topdown executive control of eating behavior. Using this paradigm, three main components of the regulatory neural system were revealed, and the region of interest, dorsolateral prefrontal cortex, was identified.
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