Abstract
A RESEARCH TEAM HAS CARried out one of the most detailed analyses to date of patterns of genetic variation in people of different ethnicities. The work represents a significant step toward the ability to identify genes that underlie individual or group variations in susceptibility to disease. Genomes of different individuals are well over 99% identical. The most typical variations are changes called single-nucleotide polymorphisms (SNPs), in which one or another of two DNA bases is found at an identical genomic location in different people. SNPs or patterns of SNPs can be associated with different traits, such as variations in disease susceptibility or drug responsiveness. However, the relationship between SNP variations and disease risk in people of different ethnicities is currently unclear. Now, Chief Scientific Officer David R. Cox of Perlegen Sciences, Mountain View, Calif., and coworkers have used DNA chip technology to analyze 1.59 million SNPs in each of 71 people from three groups: European, ...
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
